Chlorinated hydrocarbons in infertile women

被引：33

作者：

Gerhard, I ^{[1
]}

Monga, B ^{[1
]}

Krähe, J ^{[1
]}

Runnebaum, B ^{[1
]}

机构：

[1] Heidelberg Univ, Hosp Obstet & Gynecol, Dept Gynecol Endocrinol & Reprod, D-69115 Heidelberg, Germany

来源：

ENVIRONMENTAL RESEARCH | 1999年 / 80卷 / 04期

关键词：

chlorinated hydrocarbons; infertility; gynecological conditions;

D O I：

10.1006/enrs.1998.3890

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

This study was conducted to investigate the hypothesis that chlorinated hydrocarbons (CHC) may affect fertility in women. In 489 infertile women, CHC levels were measured in whole blood. Different anamnestic and clinical parameters were obtained or investigated in order to detect possible associations to CHC concentrations. CHC levels were correlated to the women's age, body mass index, and nationality. Especially in women with uterine fibroids, endometriosis, miscarriages, persistent infertility, and hormonal disturbances, elevated concentrations of chlorinated hydrocarbons with long half-lives were observed. Chlorinated hydrocarbons may play a role in female infertility and may be an underlying factor in certain gynecological conditions. (C) 1999 Academic Press.

引用

页码：299 / 310

页数：12

共 53 条

[1]

ALLEN JR, 1975, FED PROC, V34, P1675

[2] TOXICOLOGICAL CONSEQUENCES OF AROCLOR-1254 INGESTION BY FEMALE RHESUS (MACACA-MULATTA) MONKEYS .1B. PREBREEDING PHASE - CLINICAL AND ANALYTICAL LABORATORY FINDINGS [J].