Bone Graft Substitutes

被引:179
作者
Bhatt, Reena A. [2 ,3 ]
Rozental, Tamara D. [1 ]
机构
[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Orthopaed, Boston, MA 02215 USA
[2] Brown Univ, Miriam Hosp, Warren Alpert Med Sch, Dept Plast Surg, Providence, RI 02903 USA
[3] Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Dept Plast Surg, Providence, RI 02903 USA
关键词
Bone graft; Bone graft substitute; Bone substitute; Bone replacement; Autograft; Allograft; Demineralized bone matrix; Bone morphogenetic protein; Distal radius fracture; Nonunion; BETA-TRICALCIUM PHOSPHATE; TIBIAL PLATEAU FRACTURES; LUMBAR SPINE FUSION; RANDOMIZED CLINICAL-TRIAL; DISTAL RADIUS FRACTURES; ORTHOPEDIC TRAUMA; EXTERNAL FIXATION; NORIAN SRS; FOLLOW-UP; HYDROXYAPATITE;
D O I
10.1016/j.hcl.2012.08.001
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
100224 [整形外科学];
摘要
Replacement of missing bone stock is a reconstructive challenge to upper extremity surgeons and decision-making with regards to available choices remains difficult. Preference is often given to autograft in the form of cancellous, cortical, or cortico-cancellous grafts from donor sites. However, the available volume from such donor sites is limited and fraught with potential complications. Advances in surgical management and medical research have produced a wide array of potential substances that can be used for bone graft substitute. Considerations in selecting bone grafts and substitutes include characteristic capabilities, availability, patient morbidity, immunogenicity, potential disease transmission, and cost variability.
引用
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页码:457 / +
页数:13
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