Macrolide and tetracycline resistance and molecular relationships of clinical strains of Streptococcus agalactiae

被引：30

作者：

Culebras, E ^{[1
]}

Rodriguez-Avial, I ^{[1
]}

Betriu, C ^{[1
]}

Redondo, M ^{[1
]}

Picazo, JJ ^{[1
]}

机构：

[1] Hosp Univ San Carlos, Dept Clin Microbiol, Madrid 28040, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 05期

关键词：

D O I：

10.1128/AAC.46.5.1574-1576.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Mechanisms for tetracycline and macrolide resistance in 54 isolates of erythromycin-resistant Streptococcus agalactiae were analyzed by PCR. The erm(B), erm (A), and mef(A) genes, either alone or in combination, were detected in all the erythromycin-resistant isolates. The tet(M) and tet(O) genes were responsible for tetracycline resistance. Random amplification of polymorphic DNA indicated different clonal origins of the isolates.

引用

收藏

页码：1574 / 1576

页数：3

相关论文

共 27 条

[1] Presence of mefA and mefE genes in Streptococcus agalactiae [J].

Arpin, C ;

Daube, H ;

Tessier, F ;

Quentin, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (04) :944-946

[2] TETRACYCLINES, MOLECULAR AND CLINICAL ASPECTS [J].

CHOPRA, I ;

HAWKEY, PM ;

HINTON, M .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1992, 29 (03) :245-277

[3] Host range of the ermF rRNA methylase gene in bacteria of human and animal origin [J].

Chung, WSO ;

Werckenthin, C ;

Schwarz, S ;

Roberts, MC .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1999, 43 (01) :5-14

[4] Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes [J].

Clancy, J ;

Petitpas, J ;

DibHajj, F ;

Yuan, W ;

Cronan, M ;

Kamath, AV ;

Bergeron, J ;

Retsema, JA .

MOLECULAR MICROBIOLOGY, 1996, 22 (05) :867-879

[5] TRANSPOSABLE MULTIPLE ANTIBIOTIC-RESISTANCE IN STREPTOCOCCUS-PNEUMONIAE [J].

COURVALIN, P ;

CARLIER, C .

MOLECULAR & GENERAL GENETICS, 1986, 205 (02) :291-297

[6] Antibiotic susceptibility and mechanisms of erythromycin resistance in clinical isolates of Streptococcus agalactiae:: French multicenter study [J].

De Mouy, D ;

Cavallo, JD ;

Leclercq, R ;

Fabre, R .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (08) :2400-2402

[7] Genetic diversity of the tet(M) gene in tetracycline-resistant clonal lineages of Streptococcus pneumoniae [J].

Doherty, N ;

Trzcinski, K ;

Pickerill, P ;

Zawadzki, P ;

Dowson, CG .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (11) :2979-2984

[8] Mechanisms of macrolide resistance in clinical group B streptococci isolated in France [J].

Fitoussi, F ;

Loukil, C ;

Gros, I ;

Clermont, O ;

Mariani, P ;

Bonacorsi, S ;

Le Thomas, I ;

Deforche, D ;

Bingen, E .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (06) :1889-1891

[9] Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains [J].

Giovanetti, E ;

Montanari, MP ;

Mingoia, M ;

Varaldo, PE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (08) :1935-1940

[10] In vitro activity of ketolides telithromycin and HMR 3004 against Italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility [J].

Giovanetti, E ;

Montanari, MP ;

Marchetti, F ;

Varaldo, PE .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 46 (06) :905-908