Bridging the gap: are animal models consistent with clinical cancer cachexia?

被引：19

作者：

Baracos, Vickie E. ^{[1
,2
]}

机构：

[1] Univ Alberta, Div Palliat Care Med, Dept Oncol, Edmonton, AB, Canada

[2] Univ Alberta, Cross Canc Inst, Edmonton, AB, Canada

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2018年 / 15卷 / 04期

基金：

加拿大健康研究院;

关键词：

PROTEIN;

D O I：

10.1038/nrclinonc.2018.14

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Experimental research on cancer-associated cachexia is advancing at an accelerated pace while knowledge of the complex underlying biology of cachexia in humans lags behind. An unmet need exists to accelerate the identification of causal mechanisms in patients with cancer and to determine the parallels between experimental systems and distinct isotypes of human cachexia.

引用

页码：197 / 198

页数：2

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