An integrin-like protein in Candida albicans: Implications for pathogenesis

被引：23

作者：

Hostetter, MK ^{[1
]}

机构：

[1] UNIV MINNESOTA,DEPT PEDIAT,MINNEAPOLIS,MN 55455

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 06期

关键词：

D O I：

10.1016/0966-842X(96)10036-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Candida albicans is the foremost fungal pathogen in neonates, diabetics and immunocompromised people. The discovery of integrin-like proteins in this yeast and the involvement of these proteins in adhesion, morphogenesis and signal transduction suggest important roles for primitive integrins in the pathogenesis of infectious diseases, and as paradigms for signaling and differentiation in vertebrate cells.

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页码：242 / 246

页数：5

相关论文

共 40 条

[1] INTEGRINS AND OTHER CELL-ADHESION MOLECULES [J].

ALBELDA, SM ;

BUCK, CA .

FASEB JOURNAL, 1990, 4 (11) :2868-2880

[2] DISTINCT MECHANISMS OF EPITHELIAL ADHESION FOR CANDIDA-ALBICANS AND CANDIDA-TROPICALIS - IDENTIFICATION OF THE PARTICIPATING LIGANDS AND DEVELOPMENT OF INHIBITORY PEPTIDES [J].

BENDEL, CM ;

HOSTETTER, MK ;

MCCLELLAN, M .

JOURNAL OF CLINICAL INVESTIGATION, 1993, 92 (04) :1840-1849

[3] EPITHELIAL ADHESION IN YEAST SPECIES - CORRELATION WITH SURFACE EXPRESSION OF THE INTEGRIN ANALOG [J].

BENDEL, CM ;

STSAUVER, J ;

CARLSON, S ;

HOSTETTER, MK .

JOURNAL OF INFECTIOUS DISEASES, 1995, 171 (06) :1660-1663

[4]

BOUALI A, 1986, J MED VET MYCOL, V24, P345

[5] INTEGRINS AND SIGNAL-TRANSDUCTION PATHWAYS - THE ROAD TAKEN [J].

CLARK, EA ;

BRUGGE, JS .

SCIENCE, 1995, 268 (5208) :233-239

[6] CDNA CLONING AND COMPLETE PRIMARY STRUCTURE OF THE ALPHA-SUBUNIT OF A LEUKOCYTE ADHESION GLYCOPROTEIN, P150,95 [J].

CORBI, AL ;

MILLER, LJ ;

OCONNOR, K ;

LARSON, RS ;

SPRINGER, TA .

EMBO JOURNAL, 1987, 6 (13) :4023-4028

[7]

CORBI AL, 1988, J BIOL CHEM, V263, P12403

[8] SPECIFIC INTERACTION OF ASPERGILLUS-FUMIGATUS WITH FIBRINOGEN AND ITS ROLE IN CELL-ADHESION [J].

COULOT, P ;

BOUCHARA, JP ;

RENIER, G ;

ANNAIX, V ;

PLANCHENAULT, C ;

TRONCHIN, G ;

CHABASSE, D .

INFECTION AND IMMUNITY, 1994, 62 (06) :2169-2177

[9] THE I-DOMAIN IS A MAJOR RECOGNITION SITE ON THE LEUKOCYTE INTEGRIN MAC-1 (CD11B/CD18) FOR 4 DISTINCT ADHESION LIGANDS [J].

DIAMOND, MS ;

GARCIAAGUILAR, J ;

BICKFORD, JK ;

CORBI, AL ;

SPRINGER, TA .

JOURNAL OF CELL BIOLOGY, 1993, 120 (04) :1031-1043

[10]

EDWARDS JJ, 1987, J IMMUNOL, V137, P3577

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