All4312, an NtcA-regulated two-component response regulator in Anabaena sp strain PCC 7120

被引：48

作者：

Muro-Pastor, AM ^{[1
]}

Olmedo-Verd, E ^{[1
]}

Flores, E ^{[1
]}

机构：

[1] Univ Seville, CSIC, Inst Bioquim Vegetal & Fotosintesis, Seville, Spain

来源：

FEMS MICROBIOLOGY LETTERS | 2006年 / 256卷 / 01期

关键词：

all4312; ntcA; two-component; response regulator; Anabaena;

D O I：

10.1111/j.1574-6968.2006.00136.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

All4312, encoded by open reading frame all4312 in the genome of the heterocyst-forming cyanobacterium Anabaena sp. strain PCC 7120, exhibits a CheY-like receiver domain and an output domain similar to that of OmpR, characteristic of two-component response regulators. Expression of all4312 was directly regulated by NtcA, the global transcriptional regulator of nitrogen assimilation in cyanobacteria. Features characteristic of NtcA-activated promoters were also found upstream from genes encoding All4312 homologues in several other cyanobacterial genomes. Expression of all4312 was however unaffected in a mutant of hetR, which encodes a regulator triggering heterocyst development. The function of All4312 may be related to the cellular response to nitrogen deprivation.

引用

页码：171 / 177

页数：7

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