Is there a reduced risk of breast cancer among women with hip fractures?

被引：16

作者：

Ganry, O ^{[1
]}

Peng, J ^{[1
]}

Dubreuil, A ^{[1
]}

机构：

[1] CHU Amiens, Hop Nord, Serv Informat Med & Epidemiol, Dept Med Informat & Epidemiol, F-80054 Amiens 1, France

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1999年 / 15卷 / 04期

关键词：

breast cancer; estrogen; hip fracture;

D O I：

10.1023/A:1007579112855

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To test the hypothesis that osteoporosis, which results partly from long-term estrogen deficiency, is associated with a lowered risk of breast cancer, a population-based cohort study was performed in Amiens. To ascertain the incidence of breast cancer, 1300 women were followed through after a first hip fracture. Overall, 18 cases of cancer were observed cf. 21.8 expected (standardized incidence ratio (SIR): 0.82; 95% confidence interval (CI): 0.5-1.3). The results are consistent with previous studies which concluded that long-term estrogen deficiency is associated with a reduced risk of developing breast cancer.

引用

页码：313 / 315

页数：3

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