Effect of exercise training on endothelial function in men with coronary artery disease

被引:104
作者
Edwards, DG
Schofield, RS
Lennon, SL
Pierce, GL
Nichols, WW
Braith, RW
机构
[1] Univ New Hampshire, Dept Kinesiol, Durham, NH 03824 USA
[2] Univ Florida, Div Cardiovasc Med, Gainesville, FL 32611 USA
[3] Univ Florida, Ctr Exercise Sci, Gainesville, FL 32611 USA
[4] Boston Univ, Med Ctr, Myocardial Biol Unit, Boston, MA 02215 USA
关键词
D O I
10.1016/j.amjcard.2003.11.032
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The objective of this study was to investigate the effects of 12 weeks of standard cardiac rehabilitation on endothelial function, oxidative stress, and antioxidant defenses in patients with coronary artery disease. Twelve weeks of endurance exercise training led to an improvement in endothelial function as measured by brachial artery flow-mediated dilation (7.9% at baseline vs 11.1% at 12 weeks). Exercise training resulted in increased plasma nitrite and nitrate levels, increased plasma superoxide dismutase activity, and decreased oxidative stress. (C) 2004 by Excerpta Medica, Inc.
引用
收藏
页码:617 / 620
页数:4
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