Assessment by time-kill methodology of the synergistic effects of oritavancin in combination with other antimicrobial agents against Staphylococcus aureus

被引：69

作者：

Belley, Adam ^{[1
]}

Neesham-Grenon, Eve ^{[1
]}

Arhin, Francis F. ^{[1
]}

Mckay, Geoffrey A. ^{[1
]}

Parr, Thomas R., Jr. ^{[1
]}

Moeck, Gregory ^{[1
]}

机构：

[1] Targanta Therapeut Inc, St Laurent, PQ H4S 2A1, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 10期

关键词：

D O I：

10.1128/AAC.00361-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Oritavancin is a semisynthetic lipoglycopeptide in clinical development for serious gram-positive infections. This study describes the synergistic activity of oritavancin in combination with gentamicin, linezolid, moxifloxacin, or rifampin in time-kill studies against methicillin-susceptible, vancomycin-intermediate, and vancomycin-resistant Staphylococcus aureus.

引用

页码：3820 / 3822

页数：3

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