Psychoneuroimmunology of depression: Clinical implications

被引：112

作者：

Irwin, M ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Cousins Ctr Psychoneuroimmunol, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90095 USA

来源：

BRAIN BEHAVIOR AND IMMUNITY | 2002年 / 16卷 / 01期

关键词：

depression; immunity; cytokines; cardiovascular disease; infectious disease; rheumatoid arthritis; behavior; interventions;

D O I：

10.1006/brbi.2001.0654

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Psychoncuroimmunology is a field that investigates the interactions between the brain and the immune system. One important goal of this field of research is to translate basic research in order to understand how behavior affects health and resistance to disease in humans. This review evaluates the impact of depression on morbidity and mortality risk and asks whether neuroimmune mechanisms contribute to this association. Examples are drawn from three diseases: cardiovascular disease, infectious disease, and rheumatoid arthritis. Finally, the potential for biobehavioral interventions to impact psychological adaptation and the course of immune related disease is discussed. (C) 2002 Elsevier Science (USA).

引用

页码：1 / 16

页数：16

共 89 条

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