Determinants of persistent detection of human papillomavirus DNA in the uterine cervix

被引：48

作者：

Brisson, J ^{[1
]}

Bairati, I ^{[1
]}

Morin, C ^{[1
]}

Fortier, M ^{[1
]}

Bouchard, C ^{[1
]}

Christen, A ^{[1
]}

Bernard, P ^{[1
]}

Roy, M ^{[1
]}

Meisels, A ^{[1
]}

机构：

[1] UNIV LAVAL, EPIDEMIOL RES UNIT, DEPT OBSTET & GYNECOL, QUEBEC CITY, PQ G1K 7P4, CANADA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1996年 / 173卷 / 04期

关键词：

D O I：

10.1093/infdis/173.4.794

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To identify factors associated with persistence of human papillomavirus (HPV) DNA in the uterine cervix, 179 women who were 18-49 years old and who had normal cytologies and positive cervical HPV DNA tests at a routine periodic examination were analyzed. Among them, 91 (50.8%) remained HPV-positive a few months (mean, 11 weeks) later. Persistence was higher in women who had used oral contraceptives for greater than or equal to 2 years (odds ratio, 3.9; 95% confidence interval, 1.5-10.3) compared with those who never used oral contraceptives or used them for <2 years, HPV types 16, 18, and 31/33/35 appeared more persistent (odds ratio, 2.5; 95% confidence interval, 1.0-6.2) than other types. Persistence seemed to increase with virus load and decrease with increasing interval between examinations.

引用

页码：794 / 799

页数：6

共 39 条

[1] GENITAL HUMAN PAPILLOMAVIRUS INFECTION IN FEMALE UNIVERSITY-STUDENTS AS DETERMINED BY A PCR-BASED METHOD
BAUER, HM
TING, Y
GREER, CE
CHAMBERS, JC
TASHIRO, CJ
CHIMERA, J
REINGOLD, A
MANOS, MM
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1991, 265 (04): : 472 - 477
[2] BOSCH FX, 1993, CANCER EPIDEM BIOMAR, V2, P415
[3] RISK-FACTORS FOR CERVICAL INTRAEPITHELIAL NEOPLASIA - DIFFERENCES BETWEEN LOW-GRADE AND HIGH-GRADE LESIONS
BRISSON, J
MORIN, C
FORTIER, M
ROY, M
BOUCHARD, C
LECLERC, J
CHRISTEN, A
GUIMONT, C
PENAULT, F
MEISELS, A
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 140 (08) : 700 - 710
[4] THE BETHESDA SYSTEM FOR REPORTING CERVICAL VAGINAL CYTOLOGIC DIAGNOSES - REPORT OF THE 1991 BETHESDA WORKSHOP
BRODER, S
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1992, 267 (14): : 1892 - 1892
[5] PROGESTERONE AND GLUCOCORTICOID RESPONSE ELEMENTS OCCUR IN THE LONG CONTROL REGIONS OF SEVERAL HUMAN PAPILLOMAVIRUSES INVOLVED IN ANOGENITAL NEOPLASIA
CHAN, WK
KLOCK, G
BERNARD, HU
[J]. JOURNAL OF VIROLOGY, 1989, 63 (08) : 3261 - 3269
[6] DETECTION OF HUMAN PAPILLOMAVIRUS DEOXYRIBONUCLEIC-ACID BY FILTER INSITU HYBRIDIZATION DURING PREGNANCY
CZEGLEDY, J
GERGELY, L
ENDRODI, I
[J]. JOURNAL OF MEDICAL VIROLOGY, 1989, 28 (04) : 250 - 254
[7] DEVILLIERS EM, 1987, LANCET, V2, P703
[8] HUMAN PAPILLOMAVIRUS DNA IN WOMEN WITHOUT AND WITH CYTOLOGICAL ABNORMALITIES - RESULTS OF A 5-YEAR FOLLOW-UP-STUDY
DEVILLIERS, EM
WAGNER, D
SCHNEIDER, A
WESCH, H
MUNZ, F
MIKLAW, H
HAUSEN, HZ
[J]. GYNECOLOGIC ONCOLOGY, 1992, 44 (01) : 33 - 39
[9] SYMPTOMATIC AND ASYMPTOMATIC CERVICAL INFECTIONS WITH HUMAN PAPILLOMAVIRUS DURING PREGNANCY
FIFE, KH
ROGERS, RE
ZWICKL, BW
[J]. JOURNAL OF INFECTIOUS DISEASES, 1987, 156 (06) : 904 - 911
[10] THE UPSTREAM REGULATORY REGION OF THE HUMAN PAPILLOMA VIRUS-16 CONTAINS AN E2-PROTEIN-INDEPENDENT ENHANCER WHICH IS SPECIFIC FOR CERVICAL-CARCINOMA CELLS AND REGULATED BY GLUCOCORTICOID HORMONES
GLOSS, B
BERNARD, HU
SEEDORF, K
KLOCK, G
[J]. EMBO JOURNAL, 1987, 6 (12) : 3735 - 3743

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