Relationship between left ventricular hypertrophy, myocardial contractility, and load conditions in hemodialysis patients: An echocardiographic study

被引：37

作者：

Dahan, M ^{[1
]}

Siohan, P ^{[1
]}

Viron, B ^{[1
]}

Michel, C ^{[1
]}

Paillole, C ^{[1
]}

Gourgon, R ^{[1
]}

Mignon, F ^{[1
]}

机构：

[1] HOP XAVIER BICHAT,DEPT NEPHROL,PARIS,FRANCE

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 1997年 / 30卷 / 06期

关键词：

dialysis; left ventricular hypertrophy; echocardiography; volume overload; contractility;

D O I：

10.1016/S0272-6386(97)90082-2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Left ventricular hypertrophy (LVH) is common and is an independent cardiac risk factor in dialysis patients, The aim of this study was to assess hemodynamic determinants of LVH and, more particularly, the relationship between left ventricular mass, myocardial contractility, and load conditions, Eighty dialysis patients aged 51 +/- 15 years were prospectively studied by echocardiography, LVH was detected in 62 patients (78%), Left ventricular mass was significantly correlated to both end-diastolic volume (r = 0.54; P < 0.001) and end-systolic stress/end-systolic volume, an index of contractility (r = -0.66; P < 0.001), but not to systolic blood pressure or end-systolic stress, both indexes of afterload, Thus, in dialysis patients, the degree of LVH is significantly correlated with the severity of both left ventricular dilatation and contractile myocardial failure, but not with left ventricular afterload. (C) 1997 by the National Kidney Foundation, Inc.

引用

页码：780 / 785

页数：6

共 39 条

[1]

EFFECTS OF SIMULTANEOUS ALTERATIONS IN PRELOAD AND AFTERLOAD ON MEASUREMENTS OF LEFT-VENTRICULAR CONTRACTILITY IN PATIENTS WITH DILATED CARDIOMYOPATHY - COMPARISONS OF EJECTION PHASE, ISOVOLUMETRIC AND END-SYSTOLIC FORCE-VELOCITY INDEXES [J].