Amniotic membrane graft for late-onset glaucoma filtering leaks

PURPOSE: To evaluate the effectiveness and safety of amniotic membrane graft in the management of late-onset filtering bleb leaks after trabeculectomy with mitomycin C. DESIGN: Prospective, noncomparative, interventional case reports. METHODS: Two eyes of two patients with late onset filtering bleb leak received an amniotic membrane graft. RESULTS: In both patients, bleb leaks were closed successfully with amniotic membrane graft, and bleb function was maintained during the follow-up period of 34 and 14 months, respectively. CONCLUSION: Amniotic membrane graft may be considered an alternative method for treating late-onset filtering bleb leaks while maintaining bleb function. As the number of cases was small, more cases need to be accumulated to verify the usefulness of this technique. (C) 2002 by Elsevier Science Inc. All rights reserved.