Endogenous cortisol profile in patients with central serous chorioretinopathy

Aim-To study the endogenous cortisol levels in patients with central serous chorioretinopathy (CSCR). Methods-Endogenous cortisol levels in urine and plasma were determined in 30 patients with acute CSCR and compared with 30 age and sex matched controls. Results-The mean values of the 8 am plasma cortisol (29.97 mu g/dl v 18.76 mu g/dl), 11 pm plasma cortisol (22.03 mu g/dl v 13.06 mu g/dl), and 24 hour urine cortisol (11.01 mg/24 h v 7.39 mg/24 h) revealed significantly higher values in the patient group (p<0.001). Conclusions-Increased levels of endogenous cortisol are present in patients with CSCR.