Scratching the catalytic surface of mechanochemistry: a multi-component CuAAC reaction using a copper reaction vial

被引:146
作者
Cook, Teresa L. [1 ]
Walker, James A., Jr. [1 ]
Mack, James [1 ]
机构
[1] Univ Cincinnati, Cincinnati, OH 45221 USA
基金
美国国家科学基金会;
关键词
CLICK CHEMISTRY; EXPOSURE;
D O I
10.1039/c3gc36720g
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Herein we report the first copper vial catalysed CuAAC reaction. Under solvent-free mechanochemical conditions the reaction is complete in as little as 15 minutes and the triazole product isolated straight from the reaction vial with no further purification.
引用
收藏
页码:617 / 619
页数:3
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