Structures of new acidic O-specific polysaccharides of the bacterium Proteus mirabilis serogroups O26 and O30

被引：23

作者：

Shashkov, AS

Toukach, FV

Paramonov, NA

Ziolkowski, A

Senchenkova, SN

Kaca, W

Knirel, YA

机构：

[1] RUSSIAN ACAD SCI, ND ZELINSKII ORGAN CHEM INST, MOSCOW 117913, RUSSIA

[2] POLISH ACAD SCI, CTR MICROBIOL & VIROL, PL-93232 LODZ, POLAND

来源：

FEBS LETTERS | 1996年 / 386卷 / 2-3期

基金：

俄罗斯基础研究基金会;

关键词：

lipopolysaccharide; O-antigen structure; bacterial acidic polysaccharide; hexuronic acid; L-lysine; Proteus mirabilis;

D O I：

10.1016/0014-5793(96)00454-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The polysaccharide chains of the lipopolysaccharides of the Proteus mirabilis serogroups O26 and O30 were studied using sugar and methylation analysis and H-1 and C-13 NMR spectroscopy, including two-dimensional correlation spectroscopy and rotating-frame NOE spectroscopy, The polysaccharides mere found to be acidic due to the presence of D-galacturonic acid and its amide with L-lysine in serogroup O26 or D-glucuronic acid in serogroup O30, and the structures of their tetrasaccharide repeating units were established, The O26-specific polysaccharide is structurally and serologically related to the O-specific polysaccharide of P. Mirabilis O28, which includes amides of D-GalA with L-lysine and L-serine [Radziejewska-Lebrecht, J. et al.(1995) fur. J. Biochem. 230, 705-712].

引用

页码：247 / 251

页数：5

共 29 条

[1] PREDICTION OF ANTI AND GAUCHE VICINAL PROTON-PROTON COUPLING-CONSTANTS IN CARBOHYDRATES - A SIMPLE ADDITIVITY RULE FOR PYRANOSE RINGS [J].