Do thiazolidinediones cause heart failure? A critical review

被引:27
作者
Tang, WHW [1 ]
机构
[1] Cleveland Clin Fdn, Dept Cardiovasc Med, Sect Heart Failure & Cardiac Transplantat, Cleveland, OH 44195 USA
关键词
D O I
10.3949/ccjm.73.4.390
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Concern has been raised about whether the fluid retention caused by thiazolidinediones (TZDs, ie, rosiglitazone and pioglitazone) can cause or exacerbate congestive heart failure. Although fluid retention is a worrisome side effect of TZDs, current evidence does not link fluid retention caused by TZDs with worsening heart function. TZDs have many benefits for patients with diabetes and can even be used cautiously in patients with mild heart failure, with careful monitoring of. volume status.
引用
收藏
页码:390 / 397
页数:8
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