A method to adjust radiation dose-response relationships for clinical risk factors

被引：12

作者：

Appelt, Ane L. ^{[1
,2
]}

Vogelius, Ivan R. ^{[3
]}

机构：

[1] Vejle Sygehus, Dept Oncol, DK-7100 Vejle, Denmark

[2] Univ So Denmark, Odense, Denmark

[3] Univ Copenhagen, Dept Radiat Oncol, Rigshosp, DK-1168 Copenhagen, Denmark

来源：

RADIOTHERAPY AND ONCOLOGY | 2012年 / 102卷 / 03期

关键词：

Normal tissue complications; Radiotherapy; Modelling; Dose-response relationship; Radiation pneumonitis;

D O I：

10.1016/j.radonc.2011.08.031

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Several clinical risk factors for radiation induced toxicity have been identified in the literature. Here, we present a method to quantify the effect of clinical risk factors on radiation dose-response curves and apply the method to adjust the dose-response for radiation pneumonitis for patients with/without pre-existing pulmonary co-morbidities. (c) 2011 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 102 (2012) 352-354

引用

页码：352 / 354

页数：3

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