Antidepressant prescription and suicide rates: Effect of age and gender

被引：26

作者：

Kalmar, Sandor ^{[2
]}

Szanto, Katalin ^{[1
]}

Rihmer, Zoltan ^{[3
,4
]}

Mazumdar, Sati ^{[5
]}

Harrison, Katrin ^{[1
]}

Mann, J. John ^{[6
,7
]}

机构：

[1] Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA

[2] Semmelweis Hosp, Kiskunhalas, Hungary

[3] Semmelweis Univ, H-1085 Budapest, Hungary

[4] Natl Inst Psychiat & Neurol, Budapest, Hungary

[5] Univ Pittsburgh, Sch Publ Hlth, Pittsburgh, PA 15260 USA

[6] Columbia Univ, Dept Psychiat, Div Neurosci, New York, NY 10027 USA

[7] New York State Psychiat Inst & Hosp, New York, NY 10032 USA

来源：

SUICIDE AND LIFE-THREATENING BEHAVIOR | 2008年 / 38卷 / 04期

关键词：

D O I：

10.1521/suli.2008.38.4.363

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

To determine whether the effect of antidepressant exposure on suicide rate is modified by age and gender in Hungary, annual anti depressant prescription rates and suicide rates of about 10 million inhabitants between 1999-2005 were analyzed by age and gender groups. The suicide rate was inversely related to the increased use of antidepressants in both genders. The strongest association was found in the oldest age groups, where the increase in antidepressant use was highest, while there was no association in the under 20 or 50-69 age groups in either gender. Antidepressant prescription rate was related to suicide rate after controlling for divorce rate or unemployment rate, but not after controlling for alcohol consumption rate.

引用

页码：363 / 374

页数：12

共 33 条

[1] Adherence to antidepressant treatment among privately insured patients diagnosed with depression [J].

Akincigil, Ayse ;

Bowblis, John R. ;

Levin, Carrie ;

Walkup, James T. ;

Jan, Saira ;

Crystal, Stephen .

MEDICAL CARE, 2007, 45 (04) :363-369

[2] Provider and patient characteristics associated with antidepressant nonadherence: The impact of provider specialty [J].

Bambauer, Kara Zivin ;

Soumerai, Stephen B. ;

Adams, Alyce S. ;

Zhang, Fang ;

Ross-Degnan, Dennis .

JOURNAL OF CLINICAL PSYCHIATRY, 2007, 68 (06) :867-873

[3] Antidepressant drug use in Italy since the introduction of SSRIs: national trends, regional differences and impact on suicide rates [J].

Barbui, C ;

Campomori, A ;

D'Avanzo, B ;

Negri, E ;

Garattini, S .

SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, 1999, 34 (03) :152-156

[4] 100 CASES OF SUICIDE - CLINICAL ASPECTS [J].

BARRACLOUGH, B ;

BUNCH, J ;

NELSON, B ;

SAINSBURY, P .

BRITISH JOURNAL OF PSYCHIATRY, 1974, 125 (OCT) :355-373

[5] The sales of antidepressants and suicide rates in Norway and its counties 1980-2004 [J].

Bramness, Jorgen G. ;

Walby, Fredrik A. ;

Tverdal, Aage .

JOURNAL OF AFFECTIVE DISORDERS, 2007, 102 (1-3) :1-9

[6] Antidepressant medication and suicide in Sweden [J].

Carlsten, A ;

Waern, M ;

Ekedahl, A ;

Ranstam, J .

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2001, 10 (06) :525-530

[7] Psychological autopsy studies of suicide: a systematic review [J].

Cavanagh, JTO ;

Carson, AJ ;

Sharpe, M ;

Lawrie, SM .

PSYCHOLOGICAL MEDICINE, 2003, 33 (03) :395-405

[8]

Conwell Y, 1996, AM J PSYCHIAT, V153, P1001

[9] The relationship between antidepressant medication use and rate of suicide [J].

Gibbons, RD ;

Hur, K ;

Bhaumik, DK ;

Mann, JJ .

ARCHIVES OF GENERAL PSYCHIATRY, 2005, 62 (02) :165-172

[10] Antidepressants and suicide risk in the United States, 1985-1999 [J].

Grunebaum, MF ;

Ellis, SP ;

Li, SH ;

Oquendo, MA ;

Mann, JJ .

JOURNAL OF CLINICAL PSYCHIATRY, 2004, 65 (11) :1456-1462

← 1 2 3 4 →