High-density nucleoside analog probe arrays for enhanced hybridization

被引：14

作者：

Fidanza, JA ^{[1
]}

McGall, GH ^{[1
]}

机构：

[1] Affymetrix Inc, Santa Clara, CA 95051 USA

来源：

NUCLEOSIDES & NUCLEOTIDES | 1999年 / 18卷 / 6-7期

关键词：

D O I：

10.1080/07328319908044695

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA probe arrays were synthesized with analogs of 2,6-diaminopurine and 2'-O-methyl-thymidine in place of A and T. AT-rich GeneChip(R) test arrays containing 14-mer or 20-mer analog probes improved hybridization to fluorescently-labeled RNA sequences under stringent conditions.

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收藏

页码：1293 / 1295

页数：3

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