Republished viewpoint: Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype

被引：45

作者：

Berenbaum, Francis ^{[1
]}

机构：

[1] Univ Paris 06, Hop St Antoine, APHP, Dept Rheumatol, Paris, France

来源：

POSTGRADUATE MEDICAL JOURNAL | 2012年 / 88卷 / 1038期

关键词：

GLYCATION END-PRODUCTS; METABOLIC SYNDROME; OXIDATIVE STRESS; ARTICULAR CHONDROCYTES; GLUCOSE-TRANSPORT; KNEE; CARTILAGE; HYPERGLYCEMIA; INFLAMMATION; ACTIVATION;

D O I：

10.1136/pgmj.2010.146399rep

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Several epidemiological and experimental data support the hypothesis that diabetes could be an independent risk factor for osteoarthritis (OA), at least in some patients, leading to the concept of a diabetes-induced OA phenotype. If confirmed, this new paradigm will have a dramatic impact on prevention of QA intiation and progression.

引用

页码：240 / 242

页数：3

共 38 条

[1]

A Mobasheii, 2008, ADV ANAT EMBRYOL CEL, P200

[2]

FACTORS ASSOCIATED WITH OSTEO-ARTHRITIS OF THE KNEE IN THE 1ST NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEY (HANES-I) - EVIDENCE FOR AN ASSOCIATION WITH OVERWEIGHT, RACE, AND PHYSICAL DEMANDS OF WORK [J].