Brief Report: Relationship Between Non-verbal IQ and Gender in Autism

被引：71

作者：

Banach, Ryan ^{[5
]}

Thompson, Ann ^{[4
]}

Szatmari, Peter ^{[1
,4
]}

Goldberg, Jeremy ^{[4
]}

Tuff, Lawrence ^{[4
]}

Zwaigenbaum, Lonnie ^{[3
]}

Mahoney, William ^{[2
]}

机构：

[1] McMaster Univ, Offord Ctr Child Studies, Hamilton, ON, Canada

[2] McMaster Univ, Dept Pediat, Hamilton, ON, Canada

[3] Univ Alberta, Dept Pediat, Edmonton, ON, Canada

[4] McMaster Univ, Dept Psychiat & Behav Neurosci, Hamilton, ON, Canada

[5] McMaster Univ, Dept Family Med, Hamilton, ON L8S 4L8, Canada

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2009年 / 39卷 / 01期

基金：

加拿大健康研究院;

关键词：

Autism; IQ; Gender; Genetic; SEX-DIFFERENCES; INDIVIDUALS; DISORDERS;

D O I：

10.1007/s10803-008-0612-4

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

It has been proposed that females at risk for autism are protected in some way, so that only those with the greatest genetic liability are affected. Consequently, affected male siblings of females with autism should be more impaired than affected male siblings of male probands. One hundred and ninety-four (194) families with a single child with autism (simplex, SPX) and 154 families with more than one child with autism (multiplex, MPX) were examined on measures of severity, including non-verbal IQ. Among SPX families, girls had lower IQ than boys, but no such differences were seen among MPX families. Similarly, the affected brothers of girls with autism were no different from affected brothers of male probands. These data suggest that MPX and SPX families differ with respect to the relationship between gender and IQ.

引用

页码：188 / 193

页数：6

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