Influence of smoking in the glutathione-S-transferase M1 deficiency-associated risk for squamous cell carcinoma of the bladder in schistosomiasis patients in Egypt

被引：12

作者：

Lafuente, A

Zakahary, MM

ElAziz, MAA

Ascaso, C

Lafuente, MJ

Trias, M

Carretero, P

机构：

[1] UNIV ASSIUT, FAC MED, DEPT BIOCHEM, ASSIUT, EGYPT

[2] UNIV ASSIUT, FAC MED, DEPT UROL, ASSIUT, EGYPT

[3] UNIV BARCELONA, HOSP CLIN, DEPT EPIDEMIOL & BIOSTAT, BARCELONA 08036, SPAIN

[4] UNIV BARCELONA, HOSP CLIN, DEPT SURG, BARCELONA 08036, SPAIN

[5] UNIV BARCELONA, HOSP CLIN, DEPT UROL, BARCELONA 08036, SPAIN

来源：

BRITISH JOURNAL OF CANCER | 1996年 / 74卷 / 05期

关键词：

glutathione-S-transferase; bladder cancer; schistosomiasis; free radical;

D O I：

10.1038/bjc.1996.445

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this study we show an effect of the glutathione-S-transferase M1 (GSTM1) null phenotype on the risk for squamous cell carcinoma (SCC)bf the bladder among male smokers in Egypt, with an adjusted odds ratio of 4.5 (95% confidence interval: 1.06-21.77). However, no overall effect of the GSTM1 null phenotype on the risk for bladder SCC was observed.

引用

页码：836 / 838

页数：3

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