Evidence for a Ras/Ral signaling cascade

被引：179

作者：

Feig, LA

Urano, T

Cantor, S

机构：

[1] Department of Biochemistry, Sackler Sch. of Biomedical Sciences, Tufts University School of Medicine, Boston

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 11期

关键词：

D O I：

10.1016/S0968-0004(96)10058-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It is becoming clear that Ras proteins mediate their diverse biological functions by binding to, and participating in, the activation of multiple downstream targets. Recent work has identified nucleotide-exchange factors for Ral-GTPases as the newest members of the set of putative Ras 'effector molecules'. This new work has also detected two potential downstream targets of Rat proteins, a novel CDC42/Rac GTPase-activating protein and a phospholipase D.

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页码：438 / 441

页数：4

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