Integrating natural product synthesis and combinatorial chemistry

被引:24
作者
Ganesan, A [1 ]
机构
[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England
关键词
D O I
10.1351/pac200173071033
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The fields of natural product total synthesis and combinatorial chemistry have major differences as well as much in common. Unique to combinatorial chemistry is the need to devise rapid and efficient methods for parallel synthesis and purification, while an area of overlap is the targeting of natural product scaffolds for combinatorial libraries. Both these aspects are illustrated with examples from our research.
引用
收藏
页码:1033 / 1039
页数:7
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