The origins of protein phosphorylation

被引:834
作者
Cohen, P [1 ]
机构
[1] Univ Dundee, Sch Life Sci, MRC, Prot Phosphorylat Unit, Dundee DD1 4HN, Scotland
基金
英国医学研究理事会;
关键词
D O I
10.1038/ncb0502-e127
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The reversible phosphorylation of proteins is central to the regulation of most aspects of cell function but, even after the first protein kinase was identified, the general significance of this discovery was slow to be appreciated. Here I review the discovery of protein phosphorylation and give a personal view of the key findings that have helped to shape the field as we know it today.
引用
收藏
页码:E127 / E130
页数:4
相关论文
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