This practice analysis introduces the Birmingham Cognitive Screen (BCoS), a comprehensive screening tool for stroke survivors including individuals with aphasia and visuospatial neglect. A case study is used to demonstrate how the cognitive profiles created by the multiple-domain assessment at different time points can reduce the need to use multiple standardised assessments to check relative deficits and residual abilities, as well as to guide the rehabilitation process, educate the stroke survivor and family, monitor improvement in impairment and help the therapist to evaluate his or her treatment.