One- and two-sample nonparametric inference procedures in the presence of a mixture of independent and dependent censoring

被引:11
作者
Park, Y
Tian, L
Wei, LJ
机构
[1] Harvard Univ, Dept Biostat, Boston, MA 02115 USA
[2] Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA
关键词
competing risks; martingale; sensitivity analysis; simultaneous confidence interval; survival analysis;
D O I
10.1093/biostatistics/kxj005
中图分类号
Q [生物科学];
学科分类号
07 [理学]; 0710 [生物学]; 09 [农学];
摘要
In survival analysis, the event time T is often subject to dependent censorship. Without assuming a parametric model between the failure and censoring times, the parameter Theta of interest, for example, the survival function of T, is generally not identifiable. On the other hand, the collection Omega of all attainable values for Theta may be well defined. In this article, we present nonparametric inference procedures for Omega in the presence of a mixture of dependent and independent censoring variables. By varying the criteria of classifying censoring to the dependent or independent category, our proposals can be quite useful for the so-called sensitivity analysis of censored failure times. The case that the failure time is subject to possibly dependent interval censorship is also discussed in this article. The new proposals are illustrated with data from two clinical studies on HIV-related diseases.
引用
收藏
页码:252 / 267
页数:16
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