Dykellic acid, a novel apoptosis inhibitor from Westerdykella multispora F50733

被引：14

作者：

Lee, HJ

Lee, CH

Chung, MC

Chun, HK

Rhee, JS

Kho, YH

机构：

[1] Korea Res Inst Biosci & Biotechnol, Taejon 305600, South Korea

[2] Korea Adv Inst Sci & Technol, Taejon 305701, South Korea

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(99)01367-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel apoptosis inhibitor, dykellic acid (1), was isolated from the fermentation broth of Westerdykella multispora F50733. The structure of 1 was elucidated by spectral and X-ray crystallographic data. Compound 1 inhibited the etoposide-induced apoptosis of human monocytic leukemia U937 cells. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6949 / 6950

页数：2