Two-step conversion of 2-substituted furans into gamma-oxo-alpha,beta-unsaturated carboxylic acids. Formal synthesis of (+)-patulolide A and (-)-pyrenophorin

被引：16

作者：

Kobayashi, Y

Kishihara, K

Watatani, K

机构：

[1] Dept. of Biomolecular Engineering, Tokyo Institute of Technology, Yokohama 226, 4259 Nagatsuta-cho, Midori-ku

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 25期

关键词：

D O I：

10.1016/0040-4039(96)00857-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

NBS oxidation of 2-substituted furans 9 and 15 followed by further oxidation of the enals with NaClO2 afforded the acids II and 17 in good yields, which are the intermediates of(+)-patulolide A and (-)-pyrenophorin, respectively. Copyright (C) 1996 Elsevier Science Ltd

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页码：4385 / 4388

页数：4

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