Flavonoids: Prospective Drug Candidates

被引：310

作者：

Cazarolli, Luisa Helena

Zanatta, Leila

Alberton, Elga Heloisa

Reis Bonorino Figueiredo, Maria Santos

Folador, Poliane

Damazio, Rosangela Guollo

Pizzolatti, Moacir Geraldo ^{[2
]}

Mena Barreto Silva, Fatima Regina ^{[1
]}

机构：

[1] Univ Fed Santa Catarina, Ctr Ciencias Biol, Dept Bioquim, BR-88040970 Florianopolis, SC, Brazil

[2] Ctr Ciencias Fis & Matemat, Dept Quim, BR-88040970 Florianopolis, SC, Brazil

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2008年 / 8卷 / 13期

关键词：

Flavonoids; medicinal properties; absorption; disease;

D O I：

10.2174/138955708786369564

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The purpose of this review is to discuss the recent developments related to the chemistry and medicinal properties of flavonoids. Major flavonoids that show well categorized structures and well defined structure function-relationships are: flavans, flavanones, flavones, flavanonols, flavonols, catechins, anthocyanidins and isoflavone. The biological properties of flavonoids include antioxidant, anti-inflamatory, antitumoral, antiviral and antibacterial, as well as a direct cytoprotective effect on coronary and vascular systems, the pancreas and the liver. These characteristics place them among the most attractive natural substances available to enrich the current therapy options.

引用

页码：1429 / 1440

页数：12

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