Study on biodegradable polymer. 3. Synthesis and characterization of poly(DL-lactic acid)-co-poly(ethylene glycol)-co-poly(L-lysine) copolymer

被引：17

作者：

Deng, XM ^{[1
]}

Liu, Y ^{[1
]}

Yuan, ML ^{[1
]}

机构：

[1] Acad Sinica, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China

来源：

EUROPEAN POLYMER JOURNAL | 2002年 / 38卷 / 07期

基金：

中国国家自然科学基金;

关键词：

sythesis; lactic acid anhydrosulphite; amino acid-N-carboxyl anhydride; methoxypolyoxyethylene amine;

D O I：

10.1016/S0014-3057(02)00017-4

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The synthesis of poly(DL-lactic acid)-co-poly(ethylene glycol)-co-poly(L-lysine) copolymer was investigated by the reaction of amino acid-N-carboxy anhydride with lactic acid anhydrosulphite and methoxypolyoxyethylene amine (MPEG-NH2). The successful synthesis was obtained after adding dibutylmegnesium into the system. The product was proved to be copolymer. The solubility of the polymer revealed that it was ionic polymer. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1435 / 1441

页数：7

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