Isochromosome 7q in adult Wilms' tumor

被引：13

作者：

Fletcher, JA ^{[1
]}

Renshaw, AA ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, BOSTON, MA USA

来源：

CANCER GENETICS AND CYTOGENETICS | 1996年 / 86卷 / 02期

关键词：

D O I：

10.1016/0165-4608(95)00172-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We describe cytogenetic and histologic findings in a Wilms' tumor resected from a 37-year-old man. The tumor karyotype was 45,X,-Y,i(7)(q10). These findings are notable because overrepresentation of chromosome 7 long arm material, i(7)(q10) in particular has been described recently as a nonrandom event in pediatric Wilms' tumors. The present case suggests a shared genetic pathway in the initiation or progression of some pediatric and adult Wilms' tumors.

引用

页码：168 / 169

页数：2

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