Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension

被引：20

作者：

Chen, Hongyan ^{[1
]}

Dai, Jianping ^{[1
,2
]}

Zhang, Xiaozhe ^{[3
]}

Wang, Kai ^{[1
]}

Huang, Shuhua ^{[4
]}

Cao, Qingtian ^{[4
]}

Wang, Hong ^{[5
]}

Liang, Yuhong ^{[5
]}

Shi, Chuanying ^{[6
]}

Li, Mengyuan ^{[1
]}

Ha, Tingting ^{[1
]}

Ai, Lin ^{[1
,2
]}

Li, Shaowu ^{[1
,2
]}

Ma, Jun ^{[1
]}

Wei, Wenjuan ^{[7
]}

You, Youbo ^{[7
]}

Liu, Zhenyu ^{[7
]}

Tian, Jie ^{[7
]}

Bai, Lijun ^{[8
]}

机构：

[1] Capital Med Univ, Beijing Tiantan Hosp, Dept Radiol, Beijing 100050, Peoples R China

[2] Beijing Neurosurg Inst, Beijing 100050, Peoples R China

[3] Capital Med Univ, Beijing Tiantan Hosp, Dept Pain, Beijing 100050, Peoples R China

[4] China North Vehicle Res Inst Workers Hosp, Dept Med, Beijing 100072, Peoples R China

[5] Tiantan Community Hlth Serv Ctr, Beijing 100061, Peoples R China

[6] Capital Med Univ, Beijing Tiantan Hosp, Ultrason Ctr, Beijing 100050, Peoples R China

[7] Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China

[8] Xi An Jiao Tong Univ, Sch Life Sci & Technol, Key Lab Biomed Informat Engn, Minist Educ,Dept Biomed Engn, Xian 710049, Peoples R China

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2013年 / 2013卷

基金：

北京市自然科学基金; 中国国家自然科学基金;

关键词：

STIMULATION;

D O I：

10.1155/2013/808971

中图分类号：

R [医药、卫生];

学科分类号：

100218 [急诊医学];

摘要：

The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. The acupuncture group received a continuous five-day acupuncture treatment and undertook three resting-state fMRI scans and 24-hour ambulatory blood pressure monitoring (ABPM) as well as SF-36 questionnaires before, after, and one month after acupuncture treatment. The control group undertook fMRI scans and 24-hour ABPM. For verum acupuncture, average blood pressure (BP) and heart rate (HR) decreased after treatment but showed no statistical differences. There were no significant differences in BP and HR between the acupuncture and control groups. Notably, SF-36 indicated that bodily pain (P = 0.005) decreased and vitality (P = 0.036) increased after acupuncture compared to the baseline. The hypothalamus-related brain network showed increased functional connectivity with the medulla, brainstem, cerebellum, limbic system, thalamus, and frontal lobes. In conclusion, short-term acupuncture did not decrease BP significantly but appeared to improve body pain and vitality. Acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem.

引用

页数：9

共 47 条

[1]

Abele-Brehm A, 1986, DIAGNOSTICA, V32, P209

[2]

[Anonymous], 2012, World Health Statistics 2012

[3]

[Anonymous], 1981, The state-trait anxiety inventory

[4]

Acupuncture modulates temporal neural responses in wide brain networks: evidence from fMRI study [J].