Germline development in vertebrates and invertebrates

被引：243

作者：

Saffman, EE ^{[1
]}

Lasko, P ^{[1
]}

机构：

[1] McGill Univ, Dept Biol, Montreal, PQ H3A 1B1, Canada

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 1999年 / 55卷 / 8-9期

关键词：

germline; germ plasm; migration; totipotency; primordial germ cells;

D O I：

10.1007/s000180050363

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In all animals information is passed from parent to offspring via the germline, which segregates from the soma early in development and undergoes a complex developmental program to give rise to the adult gametes. Many aspects of germline development have been conserved throughout the animal kingdom. Here we review the unique properties of germ cells, the initial determination of germ cell fates, the maintenance of germ cell identity, the migration of germ cells to the somatic gonadal primordia and the proliferation of germ cells during development invertebrates and invertebrates. Similarities in germline development in such diverse organisms as Drosophila melanogaster, Caenorhabditis elegans, Xenopus laevis and Mus musculus will be highlighted.

引用

页码：1141 / 1163

页数：23

共 233 条

[1] Early stages in male germ cell differentiation in the mouse - Review article [J].