Could abatacept directly target expanded plasmablasts in IgG4-related disease?

被引:10
作者
Alegria, Guillermo Carvajal [1 ,2 ]
Pochard, Pierre [1 ]
Pers, Jacques-Olivier [1 ]
Cornec, Divi [1 ,2 ]
机构
[1] European Univ Brittany, INSERM, ESPRI, ERI29,EA2216, Brest, France
[2] CHRU Brest, Serv Rhumatol, Brest, France
关键词
RHEUMATOID-ARTHRITIS; SJOGRENS-SYNDROME; B-CELLS; ACTIVATION; EFFICACY; SUBSETS;
D O I
10.1136/annrheumdis-2016-210400
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:E73 / U5
页数:2
相关论文
共 18 条
[1]
Brief Report Number of Circulating Follicular Helper 2 T Cells Correlates With IgG4 and Interleukin-4 Levels and Plasmablast Numbers in IgG4-Related Disease [J].
Akiyama, Mitsuhiro ;
Suzuki, Katsuya ;
Yamaoka, Kunihiro ;
Yasuoka, Hidekata ;
Takeshita, Masaru ;
Kaneko, Yuko ;
Kondo, Harumi ;
Kassai, Yoshiaki ;
Miyazaki, Takahiro ;
Morita, Rimpei ;
Yoshimura, Akihiko ;
Takeuchi, Tsutomu .
ARTHRITIS & RHEUMATOLOGY, 2015, 67 (09) :2476-2481
[2]
Abatacept (CTLA-4IG) treatment reduces the migratory capacity of monocytes in patients with rheumatoid arthritis [J].
Bonelli, M. ;
Ferner, E. ;
Goeschl, L. ;
Blueml, S. ;
Hladik, A. ;
Karonitsch, T. ;
Kiener, H. P. ;
Byrne, R. ;
Niederreiter, B. ;
Steiner, C. W. ;
Rath, E. ;
Bergmann, M. ;
Smolen, J. S. ;
Scheinecker, C. .
ARTHRITIS AND RHEUMATISM, 2013, 65 (03) :599-607
[3]
The clinical spectrum of IgG4-related disease [J].
Brito-Zeron, Pilar ;
Ramos-Casals, Manuel ;
Bosch, Xavier ;
Stone, John H. .
AUTOIMMUNITY REVIEWS, 2014, 13 (12) :1203-1210
[4]
Rituximab for IgG4-related disease: a prospective, open-label trial [J].
Carruthers, Mollie N. ;
Topazian, Mark D. ;
Khosroshahi, Arezou ;
Witzig, Thomas E. ;
Wallace, Zachary S. ;
Hart, Philip A. ;
Deshpande, Vikram ;
Smyrk, Thomas C. ;
Chari, Suresh ;
Stone, John H. .
ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 (06) :1171-1177
[5]
Advances in CTLA-4-Ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis [J].
Cutolo, Maurizio ;
Nadler, Steven G. .
AUTOIMMUNITY REVIEWS, 2013, 12 (07) :758-767
[6]
B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease [J].
Della-Torre, Emanuel ;
Feeney, Eoin ;
Deshpande, Vikram ;
Mattoo, Hamid ;
Mahajan, Vinay ;
Kulikova, Maria ;
Wallace, Zachary S. ;
Carruthers, Mollie ;
Chung, Raymond T. ;
Pillai, Shiv ;
Stone, John H. .
ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 (12) :2236-2243
[7]
Abatacept efficacy in rheumatoid arthritis is dependent upon baseline blood B-cell levels [J].
Gazeau, Pierre ;
Devauchelle-Pensec, Valerie ;
Pochard, Pierre ;
Pers, Jacques-Olivier ;
Saraux, Alain ;
Renaudineau, Yves ;
Cornec, Divi .
RHEUMATOLOGY, 2016, 55 (06) :1138-1140
[8]
The changing faces of IgG4-related disease: Clinical manifestations and pathogenesis [J].
Islam, Arshia Duza ;
Selmi, Carlo ;
Datta-Mitra, Ananya ;
Sonu, Rebecca ;
Chen, Mingyi ;
Gershwin, M. Eric ;
Raychaudhuri, Siba P. .
AUTOIMMUNITY REVIEWS, 2015, 14 (10) :914-922
[9]
Activation of Syk in Peripheral Blood B Cells in Patients With Rheumatoid Arthritis A Potential Target for Abatacept Therapy [J].
Iwata, Shigeru ;
Nakayamada, Shingo ;
Fukuyo, Shunsuke ;
Kubo, Satoshi ;
Yunoue, Naoki ;
Wang, Sheau-Pey ;
Yoshikawa, Maiko ;
Saito, Kazuyoshi ;
Tanaka, Yoshiya .
ARTHRITIS & RHEUMATOLOGY, 2015, 67 (01) :63-73
[10]
B cell subsets and dysfunction of regulatory B cells in IgG4-related diseases and primary Sjogren's syndrome: the similarities and differences [J].
Lin, Wei ;
Jin, Lixia ;
Chen, Hua ;
Wu, Qingjun ;
Fei, Yunyun ;
Zheng, Wenjie ;
Wang, Qian ;
Li, Ping ;
Li, Yongzhe ;
Zhang, Wen ;
Zhao, Yan ;
Zeng, Xiaofeng ;
Zhang, Fengchun .
ARTHRITIS RESEARCH & THERAPY, 2014, 16 (03)