On-chip potential gradient detection with a portable capillary electrophoresis system

被引：21

作者：

Feng, HT ^{[1
]}

Wei, HP ^{[1
]}

Li, SFY ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

来源：

ELECTROPHORESIS | 2004年 / 25卷 / 06期

关键词：

capillary electrophoresis; electrochemical detection; microchip; miniaturization; portable; potential gradient detection;

D O I：

10.1002/elps.200305734

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A portable chip-CE system with potential gradient detection (PGD) was developed and applied to the determinations of alkali metals and alkaloids. The separation efficiency appeared to be satisfactory and nonaqueous capillary electrophoresis (NACE) proved to be applicable to PGD or conductivity detection. The power supplies, separation and detection were built on a device of 3 kg in weight. A branch channel near the end of the separation channel was designed to perform PGD and make the application of relatively high field strength possible. The study is the first report on the application of PGD on the microchip platform. The design of the chip-CE system shows several advantages, such as simplicity, miniaturization and wide applicability.

引用

页码：909 / 913

页数：5

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