Effects of two Prunella species on lymphocyte proliferation and nitric oxide production

被引：24

作者：

Harput, US ^{[1
]}

Saracoglu, I

Ogihara, Y

机构：

[1] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey

[2] Nagoya City Univ, Grad Sch Pharmaceut Sci, Dept Pharmacognosy, Mizuho Ku, Nagoya, Aichi 4678603, Japan

来源：

PHYTOTHERAPY RESEARCH | 2006年 / 20卷 / 02期

关键词：

Prunella vulgaris; P; laciniata; Lamiaceae; immunomodulation; antiinflammation; T-lymphocytes; nitric oxide; macrophages;

D O I：

10.1002/ptr.1805

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Water extracts of Prunella vulgaris and P. laciniata have been investigated for their immunomodulatory and antiinflammatory activities concerning their effect on the mitogenic response of murine splenocytes and nitric oxide production by murine peritoneal macrophages in vitro. It was found that both extracts stimulated the proliferation of T-lymphocytes and suppressed NO production in lipopolysaccharide-stimulated macrophages dose dependently without any cytotoxicity. Copyright (c) 2006 John Wiley & Sons, Ltd.

引用

页码：157 / 159

页数：3

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