Quantification of ephedrines in urine by column-switching high-performance liquid chromatography

被引：12

作者：

Gmeiner, G ^{[1
]}

Geisendorfer, T ^{[1
]}

Kainzbauer, J ^{[1
]}

Nikolajevic, M ^{[1
]}

Tausch, H ^{[1
]}

机构：

[1] Austrian Res Ctr, A-2444 Seibersdorf, Austria

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2002年 / 768卷 / 02期

关键词：

ephedrines;

D O I：

10.1016/S0378-4347(01)00545-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A method for the quantification of five congener ephedrines in urine samples without sample preparation was developed. The analytes were trapped on a C-18 precolumn and separated on a C-18 BDS analytical column. Baseline separation was achieved for all analytes. The method meets the requirements of the International Olympic Committee (IOC) medical commission regarding cut-off limits for positive doping cases with ephedrines. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：215 / 221

页数：7

共 9 条

[1]

[Anonymous], 38402 DIN 51

[2]

DELBEKE FT, 1991, BIOPHARM DRUG DISPOS, V12, P1243

[3] SELECTIVE DERIVATIZATION UNDER CONTROLLED CONDITIONS - WAY TO TRACE ANALYSIS OF AMINES [J].

DONIKE, M ;

DERENBACH, J .

FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1976, 279 (02) :128-129

[4]

DONIKE M, 1991, 9 WORKSH DOP AN COL

[5] DETERMINATION OF EPHEDRINES IN URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

IMAZ, C ;

CARRERAS, D ;

NAVAJAS, R ;

RODRIGUEZ, C ;

RODRIGUEZ, AF ;

MAYNAR, J ;

CORTES, R .

JOURNAL OF CHROMATOGRAPHY, 1993, 631 (1-2) :201-205

[6]

*IOC MED COMM, 2000, REACCR TEST

[7] SENSITIVE QUANTIFICATION OF PSEUDOEPHEDRINE IN HUMAN-PLASMA AND URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

NIEDER, M ;

JAEGER, H .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1988, 424 (01) :73-82

[8]

OTHA T, 1996, J CHROMATOGR B, V675, P168

[9] SIMULTANEOUS QUANTIFICATION OF EPHEDRINES IN URINE BY HIGHPERFORMANCE LIQUID-CHROMATOGRAPHY [J].

VANDERMERWE, PJ ;

BROWN, LW ;

HENDRIKZ, SE .

JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS, 1994, 661 (02) :357-361

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