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Cyclins, cyclin-dependent kinases and differentiation

被引：106
作者：
Gao, CY [1 ]
Zelenka, PS [1 ]
机构：
[1] NEI,MOL & DEV BIOL LAB,NIH,BETHESDA,MD 20892
来源：
BIOESSAYS | 1997年 / 19卷 / 04期
关键词：
D O I：
10.1002/bies.950190408
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cyclin-dependent kinases and their regulatory subunits, the cyclins, are known to regulate progression through the cell cycle. Yet these same proteins are often expressed in non-cycling, differentiated cells. This review surveys the available information about cyclins and cyclin-dependent kinases in differentiated cells and explores the possibility that these proteins may have important functions that are independent of cell cycle regulation.
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收藏
页码：307 / 315
页数：9
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