Salt consumption, reactive oxygen species and cardiovascular ageing: a hypothetical link

被引：27

作者：

Aviv, A ^{[1
]}

机构：

[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Hypertens Res Ctr, MSB, Room F-464,185 S Orange Ave, Newark, NJ 07103 USA

来源：

JOURNAL OF HYPERTENSION | 2002年 / 20卷 / 04期

关键词：

essential hypertension; salt; reactive oxygen species; ageing; sodium-pump;

D O I：

10.1097/00004872-200204000-00001

中图分类号：

R6 [外科学];

学科分类号：

1002 [临床医学]; 100210 [外科学];

摘要：

Opinions about the impact of dietary salt on blood pressure have dominated the debate regarding 'salt sensitivity', which can be broadly defined as the blood pressure response to changes in sodium intake among individuals in a population. However, the larger question is whether salt consumption exerts significant biological effects independent of changes in blood pressure. Provisional answers to this question are reviewed based on newly discovered links between sodium metabolism and the generation of reactive oxygen species. These links suggest that, in a subset of the general population, salt consumption is a determinant in cardiovascular ageing. J Hypertens 20:555-559 (C) 2002 Lippincott Williams Wilkins.

引用

页码：555 / 559

页数：5

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