Is high-sensitivity C-reactive protein an effective screening test for cardiovascular risk?

被引：49

作者：

Kushner, I

Sehgal, AR

机构：

[1] Metrohlth Med Ctr, Div Nephrol, Cleveland, OH 44109 USA

[2] Metrohlth Med Ctr, Ctr Hlth Care Res & Policy, Cleveland, OH 44109 USA

[3] Case Western Reserve Univ, Ctr Biomed Eth, Cleveland, OH 44106 USA

[4] Case Western Reserve Univ, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA

[5] Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA

[6] Case Western Reserve Univ, Dept Med, Cleveland, OH 44106 USA

来源：

ARCHIVES OF INTERNAL MEDICINE | 2002年 / 162卷 / 08期

关键词：

D O I：

10.1001/archinte.162.8.867

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

W e evaluate the suggestion that high-sensitivity C-reactive protein testing be used for risk assessment in the primary prevention of cardiovascular disease, using the criteria proposed by the Guide to Clinical Preventive Services developed by the US Preventive Services Task Force. We conclude that at present, none of the 3 major criteria-accuracy, reliability, and likelihood of beneficial intervention-are satisfied.

引用

页码：867 / 869

页数：3

共 30 条

[1] Effect of statin therapy on C-reactive protein levels - The Pravastatin Inflammation/CRP Evaluation (PRINCE): A randomized trial and cohort study [J].