The Role of Obesity in Cancer Survival and Recurrence

被引：224

作者：

Demark-Wahnefried, Wendy ^{[1
]}

Platz, Elizabeth A. ^{[2
]}

Ligibel, Jennifer A. ^{[3
]}

Blair, Cindy K. ^{[1
]}

Courneya, Kerry S. ^{[4
]}

Meyerhardt, Jeffrey A. ^{[3
]}

Ganz, Patricia A. ^{[5
,6
]}

Rock, Cheryl L. ^{[7
]}

Schmitz, Kathryn H. ^{[8
]}

Wadden, Thomas ^{[9
]}

Philip, Errol J. ^{[10
]}

Wolfe, Bruce ^{[11
]}

Gapstur, Susan M. ^{[12
]}

Ballard-Barbash, Rachel ^{[13
]}

McTiernan, Anne ^{[16
]}

Minasian, Lori ^{[14
]}

Nebeling, Linda ^{[15
]}

Goodwin, Pamela J. ^{[17
]}

机构：

[1] Univ Alabama Birmingham, Dept Nutr Sci, Birmingham, AL 35294 USA

[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[3] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA

[4] Univ Alberta, Fac Phys Educ & Recreat, Edmonton, AB, Canada

[5] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA

[6] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 USA

[7] Univ Calif San Diego, Dept Family & Prevent Med, La Jolla, CA 92093 USA

[8] Univ Penn, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA

[9] Univ Penn, Ctr Weight & Eating Disorders, Philadelphia, PA 19104 USA

[10] Mem Sloan Kettering Canc Ctr, Dept Psychiat & Behav Sci, New York, NY 10021 USA

[11] Oregon Hlth & Sci Univ, Dept Surg, Portland, OR 97201 USA

[12] Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA

[13] NCI, Appl Res Program, Bethesda, MD 20892 USA

[14] NCI, Community Oncol & Prevent Trials Res Grp, Bethesda, MD 20892 USA

[15] NCI, Behav Res Program, Bethesda, MD 20892 USA

[16] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA

[17] Univ Toronto, Mt Sinai Hosp, Dept Med, Toronto, ON M5G 1X5, Canada

来源：

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | 2012年 / 21卷 / 08期

关键词：

BODY-MASS INDEX; STAGE BREAST-CANCER; TREATMENT-RELATED TOXICITY; LIFE-STYLE INTERVENTION; III COLON-CANCER; QUALITY-OF-LIFE; PHYSICAL-ACTIVITY; GROWTH-FACTOR; WEIGHT-LOSS; POSTMENOPAUSAL WOMEN;

D O I：

10.1158/1055-9965.EPI-12-0485

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Obesity and components of energy imbalance, that is, excessive energy intake and suboptimal levels of physical activity, are established risk factors for cancer incidence. Accumulating evidence suggests that these factors also may be important after the diagnosis of cancer and influence the course of disease, as well as overall health, well-being, and survival. Lifestyle and medical interventions that effectively modify these factors could potentially be harnessed as a means of cancer control. However, for such interventions to be maximally effective and sustainable, broad sweeping scientific discoveries ranging from molecular and cellular advances, to developments in delivering interventions on both individual and societal levels are needed. This review summarizes key discussion topics that were addressed in a recent Institute of Medicine Workshop entitled, "The Role of Obesity in Cancer Survival and Recurrence"; discussions included (i) mechanisms associated with obesity and energy balance that influence cancer progression; (ii) complexities of studying and interpreting energy balance in relation to cancer recurrence and survival; (iii) associations between obesity and cancer risk, recurrence, and mortality; (iv) interventions that promote weight loss, increased physical activity, and negative energy balance as a means of cancer control; and (v) future directions. Cancer Epidermal Biomarkers Prev; 21(8); 1244-59. (c) 2012 AACR.

引用

页码：1244 / 1259

页数：16

共 142 条

[1]

Long-term mortality after gastric bypass surgery [J].

Adams, Ted D. ;

Gress, Richard E. ;

Smith, Sherman C. ;

Halverson, R. Chad ;

Simper, Steven C. ;

Rosamond, Wayne D. ;

LaMonte, Michael J. ;

Stroup, Antoinette M. ;

Hunt, Steven C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (08) :753-761

[2]

Physical Activity Guidelines Advisory Committee Report, 2008 [J].

不详 .

NUTRITION REVIEWS, 2009, 67 (02) :114-120

[3]

[Anonymous], SOVREMENNYE TENDENTS

[4]

[Anonymous], 2002, IARC HDB CANC PREV

[5]

[Anonymous], 2000, GUIDE IDENTIFICATION

[6]

Comparative Effectiveness of Weight-Loss Interventions in Clinical Practice [J].

Appel, Lawrence J. ;

Clark, Jeanne M. ;

Yeh, Hsin-Chieh ;

Wang, Nae-Yuh ;

Coughlin, Janelle W. ;

Daumit, Gail ;

Miller, Edgar R., III ;

Dalcin, Arlene ;

Jerome, Gerald J. ;

Geller, Steven ;

Noronha, Gary ;

Pozefsky, Thomas ;

Charleston, Jeanne ;

Reynolds, Jeffrey B. ;

Durkin, Nowella ;

Rubin, Richard R. ;

Louis, Thomas A. ;

Brancati, Frederick L. .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (21) :1959-1968

[7]

Understanding the breast cancer experience of women: A qualitative study of African American, Asian American, Latina and Caucasian cancer survivors [J].

Ashing-Giwa, KT ;

Padilla, G ;

Tejero, J ;

Kraemer, J ;

Wright, K ;

Coscarelli, A ;

Clayton, S ;

Williams, I ;

Hills, D .

PSYCHO-ONCOLOGY, 2004, 13 (06) :408-428

[8]

Metabolic Surgery and Cancer Protective Effects of Bariatric Procedures [J].

Ashrafian, Hutan ;

Ahmed, Kamran ;

Rowland, Simon P. ;

Patel, Vanash M. ;

Gooderham, Nigel J. ;

Holmes, Elaine ;

Darzi, Ara ;

Athanasiou, Thanos .

CANCER, 2011, 117 (09) :1788-1799

[9]

Screening for obesity in adults: Recommendations and rationale [J].

Berg, AO ;

Allan, JD ;

Frame, P ;

Homer, CJ ;

Johnson, MS ;

Klein, JD ;

Lieu, TA ;

Mulrow, CD ;

Orleans, CT ;

Peipert, JF ;

Pender, NJ ;

Siu, AL ;

Teutsch, SM ;

Westhoff, C ;

Woolf, SH .

ANNALS OF INTERNAL MEDICINE, 2003, 139 (11) :930-932

[10]

Berkow SE, 2007, NUTR REV, V65, P391, DOI 10.1111/j.1753-4887.2007.tb00317.x

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