The Perils of Alzheimer's Drug Development

被引：27

作者：

Schneider, Lon S. ^{[1
,2
,3
]}

Lahiri, Debomoy K. ^{[4
,5
]}

机构：

[1] Univ So Calif, Keck Sch Med, Dept Psychiat, Los Angeles, CA 90033 USA

[2] Univ So Calif, Keck Sch Med, Dept Neurol, Los Angeles, CA 90033 USA

[3] Univ So Calif, Keck Sch Med, Dept Gerontol, Los Angeles, CA 90033 USA

[4] Indiana Univ, Sch Med, Dept Psychiat, Indianapolis, IN 46202 USA

[5] Indiana Univ, Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA

来源：

CURRENT ALZHEIMER RESEARCH | 2009年 / 6卷 / 01期

关键词：

D O I：

10.2174/156720509787313871

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：77 / 78

页数：2

共 9 条

[1]

ALTSTIEL LD, 2002, ALZ DIS ASSOC DIS S1, V1, pS29

[2] Alzheimer's disease drug development in 2008 and beyond: Problems and opportunities [J].

Becker, Robert E. ;

Greig, Nigel H. .

CURRENT ALZHEIMER RESEARCH, 2008, 5 (04) :346-357

[3] Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease [J].

Farlow, MR ;

Lahiri, DK ;

Poirier, J ;

Davignon, J ;

Schneider, L ;

Hui, SL .

NEUROLOGY, 1998, 50 (03) :669-677

[4] Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease [J].

Kadir, Ahmadul ;

Andreasen, Niels ;

Almkvist, Ove ;

Wall, Anders ;

Forsberg, Anton ;

Engler, Henry ;

Hagman, Goran ;

Larksater, Marie ;

Winblad, Bengt ;

Zetterberg, Henrik ;

Blennow, Kaj ;

Langstrom, Bengt ;

Nordberg, Agneta .

ANNALS OF NEUROLOGY, 2008, 63 (05) :621-631

[5] Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease [J].

Poirier, J ;

Delisle, MC ;

Quirion, R ;

Aubert, I ;

Farlow, M ;

Lahiri, D ;

Hui, S ;

Bertrand, P ;

Nalbantoglu, J ;

Gilfix, BM ;

Gauthier, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (26) :12260-12264

[6] Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease [J].

Risner, M. E. ;

Saunders, A. M. ;

Altman, J. F. B. ;

Ormandy, G. C. ;

Craft, S. ;

Foley, I. M. ;

Zvartau-Hind, M. E. ;

Hosford, D. A. ;

Roses, A. D. .

PHARMACOGENOMICS JOURNAL, 2006, 6 (04) :246-254

[7]

Schneider L., 2006, COCHRANE DB SYST REV, V2, DOI DOI 10.1002/14651858.CD003155.PUB3

[8] Prevention therapeutics of dementia [J].

Schneider, Lon S. .

ALZHEIMERS & DEMENTIA, 2008, 4 (01) :S122-S130

[9]

SCHNEIDER LS, 2008, NEUROLOGICA IN PRESS, V2

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