New microcapsules based on oligoelectrolyte complexation

被引：36

作者：

Bartkowiak, A ^{[1
]}

Hunkeler, D ^{[1
]}

机构：

[1] Swiss Fed Inst Technol, Dept Chem, Lab Polymers & Biomat, CH-1015 Lausanne, Switzerland

来源：

BIOARTIFICIAL ORGANS II: TECHNOLOGY, MEDICINE, AND MATERIALS | 1999年 / 875卷

关键词：

D O I：

10.1111/j.1749-6632.1999.tb08492.x

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

A new one-step microencapsulation procedure has been developed. For the alginate/oligochitosan system the molar mass of the chitosan is a key parameter in the formation of stable, elastic capsules with high modulus, Furthermore, the selection of an optimum molar mass provides an additional degree of freedom, permitting the simultaneous regulation of mechanical properties and permeability without the need for multicomponent organic-inorganic chemistries as have been previously employed. The effects of molar mass of chitosan, its concentration, the alginate molar mass and its metal salt on the preparation, physical properties, and release characteristics of the capsules have been studied.

引用

页码：36 / 45

页数：10

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