Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats

被引：11

作者：

Chang, Kyung-Ha ^{[1
,2
]}

Won, Ran ^{[3
]}

Shim, Insop ^{[4
]}

Lee, Hyejung ^{[4
]}

Lee, Bae Hwan ^{[1
,2
]}

机构：

[1] Yonsei Univ, Coll Med, Dept Physiol, Seoul 120752, South Korea

[2] Yonsei Univ, Coll Med, Brain Korea Project Med Sci 21, Seoul 120752, South Korea

[3] Dongseo Univ, Dept Biomed Lab Sci, Div Hlth Sci, Pusan 617716, South Korea

[4] Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2012年 / 2012卷

基金：

新加坡国家研究基金会;

关键词：

NOXIOUS INHIBITORY CONTROLS; FOS PROTEIN EXPRESSION; JAW-OPENING REFLEX; C-FOS; DORSAL-HORN; SPINAL-CORD; BEHAVIORAL HYPERALGESIA; DIFFERENT FREQUENCIES; OPIOID RECEPTORS; STIMULATION;

D O I：

10.1155/2012/324039

中图分类号：

R [医药、卫生];

学科分类号：

100218 [急诊医学];

摘要：

Acupuncture was used to treat symptoms of pain in the ancient orient. The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recorded using a video camera and c-Fos immunohistochemistry was performed thereafter. Treatment of EA at BL60 significantly inhibited flinching behavior and c-fos expression induced by formalin injection into the paw, compared to a control group. These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain.

引用

页数：7

共 46 条

[1]

Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: Studies with remifentanil and lidocaine [J].