Bortezomib action in multiple myeloma: microRNA-mediated synergy (and miR-27a/CDK5 driven sensitivity)?

被引:31
作者
Ballabio, E. [1 ]
Armesto, M. [2 ]
Breeze, C. E. [1 ]
Manterola, L. [2 ]
Arestin, M. [2 ]
Tramonti, D. [1 ]
Hatton, C. S. R. [3 ]
Lawrie, C. H. [1 ,2 ,4 ]
机构
[1] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Lab Sci, Lymphoid Malignancy Res Grp, Oxford OX3 9DU, England
[2] Biodonostia Inst, Oncol Res Area, Hematooncol Grp, San Sebastian, Spain
[3] John Radcliffe Hosp, Dept Haematol, Oxford OX3 9DU, England
[4] Basque Fdn Sci, IKERBASQUE, Bilbao, Spain
来源
BLOOD CANCER JOURNAL | 2012年 / 2卷
关键词
CELLS; EXPRESSION;
D O I
10.1038/bcj.2012.31
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:e83 / e83
页数:3
相关论文
共 15 条
[1]  
Adamia S, 2009, BLOOD, V114, P883
[2]   miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma [J].
Chen, Lijuan ;
Li, Chunming ;
Zhang, Run ;
Gao, Xiao ;
Qu, Xiaoyan ;
Zhao, Min ;
Qiao, Chun ;
Xu, Jiaren ;
Li, Jianyong .
CANCER LETTERS, 2011, 309 (01) :62-70
[3]   Dent's disease [J].
Devuyst, Olivier ;
Thakker, Rajesh V. .
ORPHANET JOURNAL OF RARE DISEASES, 2010, 5
[4]   Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia [J].
Feng, Dan-Dan ;
Zhang, Hua ;
Zhang, Peng ;
Zheng, Yu-Sheng ;
Zhang, Xing-Ju ;
Han, Bo-Wei ;
Luo, Xue-Qun ;
Xu, Ling ;
Zhou, Hui ;
Qu, Liang-Hu ;
Chen, Yue-Qin .
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2011, 15 (10) :2164-2175
[5]   Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells [J].
Hideshima, Teru ;
Ikeda, Hiroshi ;
Chauhan, Dharminder ;
Okawa, Yutaka ;
Raje, Noopur ;
Podar, Klaus ;
Mitsiades, Constantine ;
Munshi, Nikhil C. ;
Richardson, Paul G. ;
Carrasco, Ruben D. ;
Anderson, Kenneth C. .
BLOOD, 2009, 114 (05) :1046-1052
[6]   Role of dicer and drosha for endothelial MicroRNA expression and angiogenesis [J].
Kuehbacher, Angelika ;
Urbich, Carmen ;
Zeiher, Andreas M. ;
Dimmeler, Stefanie .
CIRCULATION RESEARCH, 2007, 101 (01) :59-68
[7]   Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets [J].
Lewis, BP ;
Burge, CB ;
Bartel, DP .
CELL, 2005, 120 (01) :15-20
[8]   Cancer cell sensitivity to bortezomib is associated with survivin expression and p53 status but not cancer cell types [J].
Ling, Xiang ;
Calinski, Diane ;
Chanan-Khan, Asher A. ;
Zhou, Muxiang ;
Li, Fengzhi .
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2010, 29
[9]   BAG3 gene silencing sensitizes leukemic cells to Bortezomib-induced apoptosis [J].
Liu, Peng ;
Xu, Bei ;
Li, Jianyong ;
Lu, Hua .
FEBS LETTERS, 2009, 583 (02) :401-406
[10]  
Neri P., 2009, BLOOD, V114, P4918, DOI DOI 10.1182/BLOOD.V114.22.4918.4918