Ligand-independent activation of steroid receptors: New roles for old players

被引：106

作者：

Cenni, B ^{[1
]}

Picard, D ^{[1
]}

机构：

[1] Univ Geneva, Dept Biol Cellulaire, CH-1211 Geneva 4, Switzerland

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1999年 / 10卷 / 02期

关键词：

D O I：

10.1016/S1043-2760(98)00121-0

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Steroid receptors are known as ligand-regulated transcription factors, but more and move evidence indicates that several steroid receptors can be activated in the absence of cognate hormone by agents that fall into three separate groups: peptide growth factors, the neurotransmitter dopamine and other agents that activate cAMP-dependent protein kinase A, and the cyclins A and D1.

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页码：41 / 46

页数：6

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