Depression in advanced disease: a systematic review - Part 1. Prevalence and case finding

被引:289
作者
Hotopf, M
Chidgey, J
Addington-Hall, J
Ly, KL
机构
[1] Guys Kings & St Thomas Sch Med, Div Psychol Med, London SE5 8AZ, England
[2] Guys Kings & St Thomas Sch Med, Dept Palliat Care & Policy, London SE5 8AZ, England
[3] Inst Psychiat, London, England
[4] Stanford Univ, Stanford, CA 94305 USA
关键词
advanced disease; anxiety disorder; cancer; depression; depressive disorder; palliative care; screening;
D O I
10.1191/02169216302pm507oa
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Objective: To identify all literature regarding depression in patients with advanced cancer and among mixed hospice populations, and to summarise the prevalence of depression according to different definitions. Methods: A systematic review was performed using extensive electronic and hand searches. All studies with quantitative data on prevalence of depression were included and categorised according to their definition of depression. Results: We identified 46 eligible studies giving information on the prevalence of depression, and a further four which gave information on case finding. The most widely used assessment of depression was the Hospital Anxiety and Depression Scale (HADS), which gave a median prevalence of 'definite depression' (i.e., a score on the depression subscale of >10) of 29%, (interquartile range, IQR, 19.50-34.25%). Studies that used psychiatric interviews indicated a prevalence of major depressive disorder ranging from 5% to 26%, with a median of 15%. Studies were generally small (median sample size 88.5, IQR 50-108), had high numbers of nonresponders, and rarely gave confidence intervals for estimates of prevalence. Conclusions: Depression is a common problem in palliative care settings. The quality of much of the available research is poor, based on small samples of patients with very high nonparticipation rates. The clinical importance of depression is described in subsequent papers.
引用
收藏
页码:81 / 97
页数:17
相关论文
共 78 条
  • [1] RANDOMIZED CONTROLLED TRIAL OF EFFECTS OF COORDINATING CARE FOR TERMINALLY ILL CANCER-PATIENTS
    ADDINGTONHALL, JM
    MACDONALD, LD
    ANDERSON, HR
    CHAMBERLAIN, J
    FREELING, P
    BLAND, JM
    RAFTERY, J
    [J]. BRITISH MEDICAL JOURNAL, 1992, 305 (6865) : 1317 - 1322
  • [2] BAUSTISTA JAA, 1994, ATEN PRIM, V14, P555
  • [3] AN INVENTORY FOR MEASURING DEPRESSION
    BECK, AT
    ERBAUGH, J
    WARD, CH
    MOCK, J
    MENDELSOHN, M
    [J]. ARCHIVES OF GENERAL PSYCHIATRY, 1961, 4 (06) : 561 - &
  • [4] BROWN JH, 1986, AM J PSYCHIAT, V143, P208
  • [5] BRUGHA TS, 1993, BRIT J HOSP MED, V50, P175
  • [6] Quality-of-life evaluation: When do terminal cancer patients and health-care providers agree?
    Brunelli, C
    Costantini, M
    Di Giulio, P
    Gallucci, M
    Fusco, F
    Miccinesi, G
    Paci, E
    Peruselli, C
    Morino, P
    Piazza , M
    Tamburini, M
    Toscani, F
    [J]. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 1998, 15 (03) : 151 - 158
  • [7] CHAMBERLAIN JH, 1996, PALLIATIVE MED, V10, P70
  • [8] Comparison of palliative care needs of English- and non-English-speaking patients
    Chan, A
    Woodruff, RK
    [J]. JOURNAL OF PALLIATIVE CARE, 1999, 15 (01) : 26 - 30
  • [9] Chaturvedi S. K., 1994, Annals Academy of Medicine Singapore, V23, P256
  • [10] Chochinov HM, 1997, AM J PSYCHIAT, V154, P674