Sesquiterpene lactones from Ambrosia artemisiaefolia (Asteraceae)

被引：22

作者：

David, JP

Santos, AJD

Guedes, MLD

David, JM

Chai, HB

Pezzuto, JM

Angerhofer, CK

Cordell, GA ^{[1
]}

机构：

[1] Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA

[2] Univ Fed Bahia, Fac Farm, Salvador, BA, Brazil

[3] Univ Fed Bahia, Inst Biol, Salvador, BA, Brazil

[4] Univ Fed Bahia, Inst Quim, Salvador, BA, Brazil

来源：

PHARMACEUTICAL BIOLOGY | 1999年 / 37卷 / 02期

关键词：

Ambrosia artemisiaefolia; Asteraceae; antimalarial; cytotoxicity; isopaulitin; paulitin;

D O I：

10.1076/phbi.37.2.165.6077

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Paulitin and isopaulitin were isolated from Ambrosia artemisiaefolia and evaluated for their cytotoxic and antimalarial activities. The relative configuration of dumosin was also established.

引用

页码：165 / 168

页数：4

共 12 条

[1]

DELCASTILLO JB, 1981, AN QUIM C-ORG BIOQ, V77, P52

[2]

DELCASTILLO JB, 1981, ORG MAGN RESONANCE, V17, P232

[3] ANTI-INFLAMMATORY ACTIVITY OF SESQUITERPENE LACTONES AND RELATED COMPOUNDS [J].

HALL, IH ;

LEE, KH ;

STARNES, CO ;

SUMIDA, Y ;

WU, RY ;

WADDELL, TG ;

COCHRAN, JW ;

GERHART, KG .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (05) :537-542

[4] ISOLATION AND STRUCTURE OF CORONOPILIN, A NEW SESQUITERPENE LACTONE [J].

HERZ, W ;

HOGENAUER, G .

JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (12) :5011-&

[5] TUMOR INHIBITORS .69. STRUCTURE-CYTOTOXICITY RELATIONSHIPS AMONG SESQUITERPENE LACTONES [J].

KUPCHAN, SM ;

EAKIN, MA ;

THOMAS, AM .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (12) :1147-&

[6]

KUPCHAN SM, 1970, SCIENCE, V168, P366

[7] ANTITUMOR AGENTS .16. STEROIDAL ALPHA-METHYLENE-GAMMA-LACTONES [J].

LEE, KH ;

IBUKA, T ;

KIM, SH ;

VESTAL, BR ;

HALL, IH ;

HUANG, ES .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (08) :812-817

[8] TRADITIONAL MEDICINAL-PLANTS OF THAILAND .20. CYTOTOXIC AND ANTIMALARIAL BISBENZYLISOQUINOLINE ALKALOIDS FROM STEPHANIA-ERECTA [J].

LIKHITWITAYAWUID, K ;

ANGERHOFER, CK ;

CORDELL, GA ;

PEZZUTO, JM ;

RUANGRUNGSI, N .

JOURNAL OF NATURAL PRODUCTS, 1993, 56 (01) :30-38

[9] SESQUITERPENE LACTONES CONSTITUENTS OF AMBROSIA ARTEMISIIFOLIA L (COMPOSITAE) [J].

PORTER, TH ;

MABRY, TJ .

PHYTOCHEMISTRY, 1969, 8 (04) :793-&

[10] ISOLATION AND STRUCTURE DETERMINATION OF ARTEMISIIFOLIN, A NEW GERMACRANOLIDE FROM AMBROSIA-ARTEMISIIFOLIA L (COMPOSITAE) [J].

PORTER, TH ;

MABRY, TJ ;

YOSHIOKA, H ;

FISCHER, NH .

PHYTOCHEMISTRY, 1970, 9 (01) :199-&

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